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The Solvent Evaporator consists of two components: the Holder for glass scintillation vials and the Evaporation Head.
After the solid-phase synthesis is completed, target compounds are typically cleaved from the resin by a cocktail containing trifluoroacetic acid (TFA) and methylenechloride.
Products containing solutions are collected into scintillation vials.
Then the Evaporation Head is placed on the top of vials and secured by gently tightening two red screws.
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To evaporate solvents, nitrogen is blown into scintillation vials via a Luer female connector located on the side of the Evaporation Head. The Evaporation Head distributes nitrogen into individual vials.
The outlet of the Evaporation Head is connected to a waste container with a solution of bicarbonate to neutralize the TFA vapors. Alternatively, the outlet can be connected to a cold trap to condense solvent vapors.
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